A Primer Of Population Genetics Download Ebook PDF Epub Online

Author : Daniel L. Hartl
Publisher : Oxford University Press
Release : 2020-06-18
Page : 272
Category : Science
ISBN 13 : 0192607049
Description :


A Primer of Population Genetics and Genomics has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics. Recent textbooks have tended to focus on such specialized topics as the coalescent, molecular evolution, human population genetics, or genomics. This primer bucks that trend by encouraging a broader familiarity with, and understanding of, population genetics and genomics as a whole. The overview ranges from mating systems through the causes of evolution, molecular population genetics, and the genomics of complex traits. Interwoven are discussions of ancient DNA, gene drive, landscape genetics, identifying risk factors for complex diseases, the genomics of adaptation and speciation, and other active areas of current research. The principles are illuminated by numerous examples from a wide variety of animals, plants, microbes, and human populations. The approach also emphasizes learning by doing, which in this case means solving numerical or conceptual problems. The rationale behind this is that the use of concepts in problem-solving lead to deeper understanding and longer knowledge retention. This accessible, introductory textbook is aimed principally at students of various levels and abilities (from senior undergraduate to postgraduate) as well as practising scientists in the fields of population genetics, ecology, evolutionary biology, computational biology, bioinformatics, biostatistics, physics, and mathematics.


Author : Daniel L. Hartl
Publisher : Sinauer Associates, Incorporated
Release : 1988
Page : 305
Category : Population genetics
ISBN 13 :
Description :


The use of molecular methods to study genetic polymorphisms has made a familiarity with population genetics essential for any biologist whose work is at the population level. A Primer of Population Genetics, Third Edition provides a concise but comprehensive introduction to population genetics. The four chapters of the book address genetic variation, the causes of evolution, molecular population genetics, and the genetic architecture of complex traits. Chapter-end problems reinforce ideas and, while there are some equations, the emphasis is on explanation rather than derivation.


Author : Asher D. Cutter
Publisher : Oxford University Press
Release : 2019-06-06
Page : 304
Category : Science
ISBN 13 : 0192575546
Description :


What are the genomic signatures of adaptations in DNA? How often does natural selection dictate changes to DNA? How does the ebb and flow in the abundance of individuals over time get marked onto chromosomes to record genetic history? Molecular population genetics seeks to answer such questions by explaining genetic variation and molecular evolution from micro-evolutionary principles. It provides a way to learn about how evolution works and how it shapes species by incorporating molecular details of DNA as the heritable material. It enables us to understand the logic of how mutations originate, change in abundance in populations, and become fixed as DNA sequence divergence between species. With the revolutionary advances in genomic data acquisition, understanding molecular population genetics is now a fundamental requirement for today's life scientists. These concepts apply in analysis of personal genomics, genome-wide association studies, landscape and conservation genetics, forensics, molecular anthropology, and selection scans. This book introduces, in an accessible way, the bare essentials of the theory and practice of molecular population genetics.


Author : Jeffrey K. Conner
Daniel L. Hartl
Publisher : Sinauer Associates Incorporated
Release : 2004-01
Page : 304
Category : Science
ISBN 13 : 9780878932023
Description :


This book covers basic concepts in population and quantitative genetics, including measuring selection on phenotypic traits. The emphasis is on material applicable to field studies of evolution focusing on ecologically important traits. Topics addressed are critical for training students in ecology, evolution, conservation biology, agriculture, forestry, and wildlife management. Many texts in this field are too complex and mathematical to allow the average beginning student to readily grasp the key concepts. A Primer of Ecological Genetics, in contrast, employs mathematics and statistics-fully explained, but at a less advanced level-as tools to improve understanding of biological principles. The main goal is to enable students to understand the concepts well enough that they can gain entry into the primary literature. Integration of the different chapters of the book shows students how diverse concepts relate to each other.


Author : Daniel L. Hartl
Publisher :
Release : 2020
Page :
Category : Genomics
ISBN 13 : 9780191895074
Description :


This accessible primer has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.


Author : Edward O. Wilson
Honorary Curator in Entomology and University Research Professor Emeritus Edward O Wilson
Publisher : Sinauer Associates, Incorporated
Release : 1971
Page : 192
Category : Science
ISBN 13 :
Description :


How to learn population biology. Population genetics. Ecology. Biogeography: species equilibrium theory.


Author : P. W. Richards
Richard Frankham
Publisher : Cambridge University Press
Release : 1996-08-08
Page : 575
Category : Science
ISBN 13 : 9780521538275
Description :


A new and completely revised edition of a classic book on the tropical rain forest.


Author : P. W. Richards
Richard Frankham
Publisher : Cambridge University Press
Release : 1996-08-08
Page : 575
Category : Science
ISBN 13 : 9780521538275
Description :


A new and completely revised edition of a classic book on the tropical rain forest.


Author : Fred W. Allendorf
Gordon H. Luikart
Publisher : John Wiley & Sons
Release : 2012-10-05
Page : 632
Category : Science
ISBN 13 : 1118408578
Description :


Loss of biodiversity is among the greatest problems facing theworld today. Conservation and the Genetics of Populationsgives a comprehensive overview of the essential background,concepts, and tools needed to understand how genetic informationcan be used to conserve species threatened with extinction, and tomanage species of ecological or commercial importance. Newmolecular techniques, statistical methods, and computer programs,genetic principles, and methods are becoming increasingly useful inthe conservation of biological diversity. Using a balance of dataand theory, coupled with basic and applied research examples, thisbook examines genetic and phenotypic variation in naturalpopulations, the principles and mechanisms of evolutionary change,the interpretation of genetic data from natural populations, andhow these can be applied to conservation. The book includesexamples from plants, animals, and microbes in wild and captivepopulations. This second edition contains new chapters on Climate Change andExploited Populations as well as new sections on genomics, geneticmonitoring, emerging diseases, metagenomics, and more. One-third ofthe references in this edition were published after the firstedition. Each of the 22 chapters and the statistical appendix have aGuest Box written by an expert in that particular topic (includingJames Crow, Louis Bernatchez, Loren Rieseberg, Rick Shine, andLisette Waits). This book is essential for advanced undergraduate and graduatestudents of conservation genetics, natural resource management, andconservation biology, as well as professional conservationbiologists working for wildlife and habitat managementagencies. Additional resources for this book can be found at: ahref="http://www.wiley.com/go/allendorf/populations"www.wiley.com/go/allendorf/populations/a.


Author : Asher D. Cutter
Publisher :
Release :
Page :
Category : Electronic books
ISBN 13 : 9780191874826
Description :


Provides a concise, accessible introduction to the principle ideas, methods, and caveats for understanding evolution at the molecular level.


Author : John H. Gillespie
Johnh Gillespie
Publisher : JHU Press
Release : 2004-08-06
Page : 214
Category : Medical
ISBN 13 : 0801880084
Description :


This concise introduction addresses the theories behind population genetics and relevant empirical evidence, genetic drift, natural selection, nonrandom mating, quantitative genetics, and the evolutionary advantage of sex.


Author : Richard Frankham
Jonathan D. Ballou
Publisher : Cambridge University Press
Release : 2010
Page : 618
Category : Electronic books
ISBN 13 : 0521878470
Description :


This impressive author team brings the wealth of advances in conservation genetics into the new edition of this introductory text, including new chapters on population genomics and genetic issues in introduced and invasive species. They continue the strong learning features for students - main points in the margin, chapter summaries, vital support with the mathematics, and further reading - and now guide the reader to software and databases. Many new references reflect the expansion of this field. With examples from mammals, birds,...


Author : Alan R. Templeton
Publisher : Academic Press
Release : 2018-11-08
Page : 498
Category : Science
ISBN 13 : 0123860261
Description :


Human Population Genetics and Genomics provides researchers/students with knowledge on population genetics and relevant statistical approaches to help them become more effective users of modern genetic, genomic and statistical tools. In-depth chapters offer thorough discussions of systems of mating, genetic drift, gene flow and subdivided populations, human population history, genotype and phenotype, detecting selection, units and targets of natural selection, adaptation to temporally and spatially variable environments, selection in age-structured populations, and genomics and society. As human genetics and genomics research often employs tools and approaches derived from population genetics, this book helps users understand the basic principles of these tools. In addition, studies often employ statistical approaches and analysis, so an understanding of basic statistical theory is also needed. Comprehensively explains the use of population genetics and genomics in medical applications and research Discusses the relevance of population genetics and genomics to major social issues, including race and the dangers of modern eugenics proposals Provides an overview of how population genetics and genomics helps us understand where we came from as a species and how we evolved into who we are now


Author : James N. Thompson, Jr
Jenna J. Hellack
Publisher : Cambridge University Press
Release : 2007-10-01
Page :
Category : Science
ISBN 13 : 9781139465649
Description :


An invaluable student-tested study aid, this primer, first published in 2007, provides guided instruction for the analysis and interpretation of genetic principles and practice in problem solving. Each section is introduced with a summary of useful hints for problem solving and an overview of the topic with key terms. A series of problems, generally progressing from simple to more complex, then allows students to test their understanding of the material. Each question and answer is accompanied by detailed explanation. This third edition includes additional problems in basic areas that often challenge students, extended coverage in molecular biology and development, an expanded glossary of terms, and updated historical landmarks. Students at all levels, from beginning biologists and premedical students to graduates seeking a review of basic genetics, will find this book a valuable aid. It will complement the formal presentation in any genetics textbook or stand alone as a self-paced review manual.


Author : Philip W. Hedrick
Publisher : Jones & Bartlett Learning
Release : 2011-08-24
Page : 675
Category : Medical
ISBN 13 : 9780763757373
Description :


The Fourth Edition of Genetics of Populations is the most current, comprehensive, and accessible introduction to the field for advanced undergraduate and graduate students, and researchers in genetics, evolution, conservation, and related fields. In the past several years, interest in the application of population genetics principles to new molecular data has increased greatly, and Dr. Hedrick's new edition exemplifies his commitment to keeping pace with this dynamic area of study. Reorganized to allow students to focus more sharply on key material, the Fourth Edition integrates coverage of theoretical issues with a clear presentation of experimental population genetics and empirical data. Drawing examples from both recent and classic studies, and using a variety of organisms to illustrate the vast developments of population genetics, this text provides students and researchers with the most comprehensive resource in the field.


Author : Matthew Hamilton
Publisher : John Wiley & Sons
Release : 2011-09-23
Page : 424
Category : Science
ISBN 13 : 1444362453
Description :


This book aims to make population genetics approachable, logical and easily understood. To achieve these goals, the book’s design emphasizes well explained introductions to key principles and predictions. These are augmented with case studies as well as illustrations along with introductions to classical hypotheses and debates. Pedagogical features in the text include: Interact boxes that guide readers step-by-step through computer simulations using public domain software. Math boxes that fully explain mathematical derivations. Methods boxes that give insight into the use of actual genetic data. Numerous Problem boxes are integrated into the text to reinforce concepts as they are encountered. Dedicated website at www.wiley.com/go/hamiltongenetics This text also offers a highly accessible introduction to coalescent theory, the major conceptual advance in population genetics of the last two decades.


Author : Greg Gibson
Publisher : Sinauer Associates Incorporated
Release : 2014-10-01
Page : 442
Category : Science
ISBN 13 : 9781605353135
Description :


A Primer of Human Genetics is an introductory textbook designed to give students the foundation they need to understand and appreciate the extraordinary shifts in human genetics that have accompanied the arrival of genomics. The book lays out the key concepts of human evolution, quantitative genetics, and personalized medicine before describing the tools that are missing from most contemporary textbooks: genome-wide association studies, whole-genome resequencing, gene expression and epigenome profiling, and integrative genomics. The final section provides an up-to-date survey of specific findings in six major domains of human disease: immunological, metabolic, cardiovascular, cancer, neuropsychological, and aging disorders. After reading this textbook, not only will students be better equipped to read current literature, they will gain a sense of the impact that the revolution in genomics has had for our understanding of the human condition, as well as of the major trends in human genetics research. Students are assumed to have a core understanding of genetics such as would be obtained in a general genetics class. Each chapter is approximately 20 pages long, and organized under up to ten sub-headings, most of which incorporate an illustrative figure. Chapter summary points recap the key messages, and references point students to key reviews and contemporary highlights. Several of the chapters contain a single box, which provides extra material on topics such as "Consent and Responsible Conduct of Research" and "Methylation Analysis in Biology."--Publisher description.


Author : Matthew William Hahn
Publisher : Sinauer Associates, Incorporated
Release : 2018
Page : 334
Category : Molecular genetics
ISBN 13 : 9780878939657
Description :


Published by Sinauer Associates, an imprint of Oxford University Press. Provides descriptions of the methods and tools used in molecular population genetics, which has combined advances in molecular biology and genomics with mathematical and empirical findings to uncover the history of natural selection and demographic shifts in many organisms.


Author : Francisco José Ayala
University Professor and Donald Bren Professor of Biological Sciences Francisco J Ayala
Publisher : Benjamin-Cummings Publishing Company
Release : 1982
Page : 268
Category : Science
ISBN 13 :
Description :



Author : Daniel L. Hartl
Andrew G. Clark
Publisher : Sinauer Associates Incorporated
Release : 2007
Page : 652
Category : Science
ISBN 13 : 9780878933082
Description :


This edition provides a balanced presentation of theory and observation. It introduces the principles of genetics and statistics that are relevant to population studies, and examines the forces affecting genetic variation from the molecular to the organismic level.