The Biology Of Cancer Download Ebook PDF Epub Online

Author : Weinberg, Robert A.
Publisher : W.W. Norton & Company
Release : 2013-05-24
Page : 28
Category : Science
ISBN 13 : 0815345283
Description :


Incorporating the most important advances in the fast-growing field of cancer biology, the text maintains all of its hallmark features. It is admired by students, instructors, researchers, and clinicians around the world for its clear writing, extensive full-color art program, and numerous pedagogical features.


Author : Robert Allan Weinberg
Publisher : Garland Pub
Release : 2007
Page : 796
Category : Science
ISBN 13 : 9780815340782
Description :


Accompanying CD-ROM contains ... "figures from text--in PowerPoint and JPEG formats; supplementary sidebars; mini-lectures; movies."--CD-ROM label.


Author : P.R. Burch
Publisher : Springer
Release : 1976-01-31
Page : 452
Category : Medical
ISBN 13 :
Description :


Of all the diseases that afflict mankind those described as 'cancer' evoke the strongest emotions. 'Cancer' connotes pain, protracted suffering, hideous growth and death. It is widely and justifiably feared. In medically advanced countries, malignant neoplasms (the official term for cancers) account for a substantial proportion of all deaths. Out of a total of 575194 deaths in Eng land and Wales during the year 1970, some 117076-or 20·4 per cent-were attributed to neoplasms of one kind or another (Registrar General, 1972). Diseases of the circulatory system-mainly arteriosclerotic and degenerative heart disease-claimed many more victims, being responsible for some 50·6 per cent of all deaths, but our psyche evidently responds more to the manner of the disease than to the number of deaths it causes. Many of us will have witnessed the deterioration of a close friend or relative suffering from an inoperable cancer: such an experience induces a sense of hopelessness and helplessness. The feelings of sorrow and distress can be a powerful stimulus to action and they often result in dedicated and tireless research efforts. At the same time, the very strength and depth of the commitment may sometimes be incompatible with the detachment that is needed for objective analysis and a wise strategy. Not too rigorously, we reason that if only we can discover the causes of cancer, then our problems will be solved and our agonies relieved. Remove the cause: prevent the cancer. The logic exerts an irresistible appeal.


Author : Francesco Pezzella
Mahvash Tavassoli
Publisher : Oxford University Press
Release : 2019-05-02
Page : 496
Category : Medical
ISBN 13 : 0198779453
Description :


The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.


Author : Stella Pelengaris
Michael Khan
Publisher : John Wiley & Sons
Release : 2009-03-12
Page : 544
Category : Science
ISBN 13 : 1444309080
Description :


This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. Written by an international panel of researchers, specialists and practitioners in the field Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research Features up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review Supported by a dedicated website at www.blackwellpublishing.com/pelengaris An excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field


Author : Lauren Pecorino
Publisher : Oxford University Press
Release : 2012-04-26
Page : 342
Category : Medical
ISBN 13 : 019957717X
Description :


The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics offers a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents.


Author : Harold Varmus
Robert Allan Weinberg
Publisher : Times Books
Release : 1993-01-01
Page : 214
Category : Medical
ISBN 13 : 9780716750376
Description :


Discusses advances in cancer research and shows how research into the causes of cancer have led to a greater understanding of the normal biological functioning of cells


Author : Robin Hesketh
Publisher : Cambridge University Press
Release : 2013
Page : 335
Category : Medical
ISBN 13 : 1107013984
Description :


A concise overview of the fundamental concepts of cancer biology, ideal for those with little or no background in the field. From cancer epidemiology and the underlying mechanisms, through to tumour detection and treatment, the comprehensive picture revealed will enable students to move into the cancer field with confidence.


Author : Arthur B. Pardee
Gary S. Stein
Publisher : John Wiley & Sons
Release : 2011-09-20
Page : 287
Category : Medical
ISBN 13 : 1118208455
Description :



Author : Fiona Macdonald
Christopher Ford
Publisher : Taylor & Francis
Release : 2004-06-02
Page : 269
Category : Science
ISBN 13 : 1135321590
Description :


Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes may be used in the diagnosis and in determining the prognosis of a wide variety of cancers, including breast, genitourinary, lung and gastrointestinal cancer.


Author : Robert G. McKinnell
Publisher : Cambridge University Press
Release : 2006-08-28
Page : 475
Category : Medical
ISBN 13 : 0521844584
Description :


This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.


Author : Robert A Weinberg
Publisher : Basic Books
Release : 2008-08-04
Page : 176
Category : Science
ISBN 13 : 9780786724017
Description :


Cancer research has reached a major turning point. The quality and quantity of information gathered about this disease in the past twenty years has revolutionized our understanding of its origins and behavior. No one is better qualified to comment on these dramatic leaps forward than molecular biologist Robert A. Weinberg, director of one of the leading cancer research centers in the world. In One Renegade Cell , Weinberg presents an accessible and state-of-the-art account of how the disease begins and how, one day, it will be cured. Weinberg tells how the roots of cancer were uncovered in 1909 and when the first cancer-causing virus was discovered. He then moves forward to the discovery of the role of chemical carcinogens and radiation in triggering cancer, and relates the remarkable story of the discoveries of oncogenes and tumor suppressor genes, the master controllers of normal and malignant cell proliferation. This book, which presumes little prior knowledge of biology, describes the revolution in biomedical research that has finally uncovered the forces driving malignant growth. Drawing on insights that simply were not available until recently, the discoveries presented in One Renegade Cell have already begun to profoundly alter the way that we diagnose and treat human cancers.


Author : Richard Mcintosh/Mcd Biology
Publisher : Garland Science
Release : 2019-05-02
Page : 446
Category : Medical
ISBN 13 : 0429576269
Description :


Understanding Cancer is a brand-new undergraduate textbook that uses simple language and well-chosen examples to explain the biological processes that underlie cancer and inform our methods for the diagnosis and treatment of this disease. The book has been carefully designed to provide key information relevant for students seeking a broad and accessible introduction to the cancer problem, even if they have no prior training in biology or chemistry.


Author : Rita Fior
Rita Zilhão
Publisher : Springer
Release : 2019-06-27
Page : 216
Category : Medical
ISBN 13 : 3030118126
Description :


This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach. The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited. In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed. The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease


Author : Janice Gabriel
Publisher : John Wiley & Sons
Release : 2006-02-03
Page : 200
Category : Medical
ISBN 13 : 0470031638
Description :


The application of biology to the delivery of cancer care is playing an increasingly important role in the management of this group of diseases. Although there are a plethora of specialist cancer biology books, they are not aimed at nursing students and practising nurses. The aim of this book is to be an informative text for students, newly qualified nurses and practising oncology/palliative care nurses. It is also hoped that it will be a useful text for other health care professionals working in the field of cancer, so that the common questions asked by patients, and their families, can be answered with a clear understanding of the latest advancements in the management of an individual' s care.


Author : Michael Molls
Peter Vaupel
Publisher : Springer Science & Business Media
Release : 2009-03-25
Page : 367
Category : Medical
ISBN 13 : 3540743863
Description :


Te rapidly changing concepts in radiation oncology with the development of more precise - strumentation for delivery of radiation therapy and a greater emphasis on hypofractionation technologies require a very intimate knowledge of tumor biology and the infuence of various biologic factors on dose distribution within the tumor in terms of homogeneity as well as prev- tion of any late efects on normal tissue surrounding the tumor itself. Not only are these major factors in clinical practice but also the known factors of inhomogeneity of cancer cells, the impact of microenvironment in terms of radiation efect, and host factors make it mandatory to design therapeutic strategies to improve the outcome and to diminish any potential short-term or lo- term risks from the radiation therapy. Te authors have developed an outstanding text that deals with these strategies and how they would impact on established and emerging new technologies and treatment. Te context of the presentations within a multidisciplinary combined modality therapy program is incredibly - portant. In this volume, various topics are reviewed including tumor genesis, cell proliferation, - giogenesis, the physiologic characteristics of malignant tissues, invasion and adhesion, the route and role pursued in the development of metastasis, and the role of the human immune system in cancer prevention and development.


Author : Thomas Cowan
Publisher : Chelsea Green Publishing
Release : 2019-09-24
Page : 208
Category : Health & Fitness
ISBN 13 : 1603588817
Description :


"When President Nixon launched the War on Cancer with the signing of the National Cancer Act of 1971 and the allocation of billions of research dollars, it was amidst a flurry of promises that a cure was within reach. The research establishment was trumpeting the discovery of oncogenes, the genes that supposedly cause cancer. As soon as we identified them and treated cancer patients accordingly, cancer would become a thing of the past. Fifty years later it's clear that the War on Cancer has failed--despite what the cancer industry wants us to believe. New diagnoses have continued to climb; one in three people in the United States can now expect to battle cancer during their lifetime. For the majority of common cancers, the search for oncogenes has not changed the treatment: We're still treating with the same old triad of removing (surgery), burning out (radiation), or poisoning (chemotherapy). In Cancer and the New Biology of Water, Thomas Cowan, MD, argues that this failure was inevitable because the oncogene theory is incorrect--or at least incomplete--and based on a flawed concept of biology in which DNA controls our cellular function and therefore our health. Instead, Dr. Cowan tells us, the somatic mutations seen in cancer cells are the result of a cellular deterioration that has little to do with oncogenes, DNA, or even the nucleus. The root cause is metabolic dysfunction that deteriorates the structured water that forms the basis of cytoplasmic health. Despite mainstream medicine's failure to bring an end to suffering or deliver on its promises, it remains illegal for physicians to prescribe anything other than the "standard of care" for their cancer patients, despite the fact that gentler, more effective, and more promising treatments exist"--


Author : Lewis J. Kleinsmith
Publisher : Benjamin-Cummings Publishing Company
Release : 2006
Page : 312
Category : Health & Fitness
ISBN 13 :
Description :


Written for undergraduate students with diverse backgrounds and for members of the general readership interested in the "breakthroughs" announced so often, this well-illustrated text steps through basic principles of cancer biology, emphasizing the scientific evidence underneath them. Kleinsmith (molecular, cellular and developmental biology emeritus, U. of Michigan) refines what we image the word "cancer" means, then covers the profile of a cancer cell, the means by which cancer cells spread, the causes, chemicals, infectious agents, radiation, heredity, oncogenes, tumor suppression genes, screening and diagnosis, treatment, and prevention. Annotation :2006 Book News, Inc., Portland, OR (booknews.com).


Author : Harris Busch
Publisher : Academic Press
Release : 2013-10-22
Page : 656
Category : Health & Fitness
ISBN 13 : 1483216853
Description :


The Molecular Biology of Cancer discusses the state of progress in the molecular biology of cancer. The book describes the effects of anticancer agents on nucleolar ultrastructure; the role of chromosomes in the causation and progression of cancer and leukemia; the replication, modification, and repair of DNA. The text also describes the metabolism and utilization of messenger RNA and other high molecular weight RNA and low molecular weight nuclear RNA; the characteristics, structures, and functions of nuclear proteins; and the process of protein synthesis. Nucleotides are reviewed with regard to its biosynthesis, inhibition of synthesis, and development of resistance to inhibitors. The book further tackles the biochemical mechanisms of chemical carcinogenesis; the oncogenic viruses; and the molecular correlation concept. The text also demonstrates phenotypic variability as a manifestation of translational control; and plasmacytomas. Molecular biologists, virologists, pathologists, cell biologists, oncologists, pharmacologists, and students taking related courses will find the book useful.


Author : Stella Pelengaris
Michael Khan
Publisher : Wiley-Blackwell
Release : 2009-03-12
Page : 544
Category : Science
ISBN 13 : 1444309080
Description :


This comprehensive text provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment. Written by an international panel of researchers, specialists and practitioners in the field, the text discusses all aspects of cancer biology from the causes, development and diagnosis through to the treatment of cancer. Written by an international panel of researchers, specialists and practitioners in the field Covers both traditional areas of study and areas of controversy and emerging importance, highlighting future directions for research Features up-to-date coverage of recent studies and discoveries, as well as a solid grounding in the key concepts in the field Each chapter includes key points, chapter summaries, text boxes, and topical references for added comprehension and review Supported by a dedicated website at www.blackwellpublishing.com/pelengaris An excellent text for upper-level courses in the biology of cancer, for medical students and qualified practitioners preparing for higher exams, and for researchers and teachers in the field